Karen Henthorn (born 1963) is a British character actress who portrayed the role of Teresa Bryant in the long-running British soap opera Coronation Street. She appeared in the role briefly in 2007 and became a regular character in 2008. Her character was involved in major story lines. In late 2008, she left the show but returned on 13 April 2009. She then departed the show in 2010.
Henthorn was born in Oldham, Lancashire. Her roles before Coronation Street included parts in series such as The Booze Cruise, in which she played Cath Bolton, Doctors and Heartbeat. She also played Julie Haye in EastEnders in 1997–98 and Marissa Platting (Series 2 Social Worker) in the television series Shameless.

She currently teaches screen acting on the BA (Hons) Acting course at Italia Conti in Clapham and Manchester School of Theatre.

She has most recently appeared on as Teressa Ryan in TV series Dark Heart. She also recently played a teacher in the cbbc series young dracula, and plays Janet Macy on the TV series In the Flesh